"I Can't Quit You Baby" is a blues standard written by Willie Dixon and first recorded by Chicago blues guitarist Otis Rush in 1956 as Cobra Records’ debut single. It is a slow twelve-bar blues about the pull of an adulterous relationship and the struggle to end it, featuring Rush with a tight ensemble that includes Big Walter Horton on harmonica and Lafayette Leake on piano. The song was Rush’s first recording and became a chart hit, later re-recorded by Rush in 1966 with a modified Vanguard arrangement. Led Zeppelin adapted the track for their 1969 debut album, giving it a blues-rock treatment that runs about 4 minutes and 42 seconds and showcased their approach to the classic blues form. The original Cobra single is a blues staple and Rush’s version, along with Dixon’s writing, helped make the song a lasting influence in blues and rock, earning a Blues Foundation Hall of Fame induction for Rush's recording in 1994.