"Do You Know What It Means to Miss New Orleans?" is a jazz-blues standard of the Great American Songbook, with lyrics by Eddie DeLange and music by Louis Alter. The sheet music is titled "Do You Know What It Means?" The song was first heard in the 1947 film New Orleans, directed by Arthur Lubin, in a performance by Louis Armstrong with Billie Holiday singing. Armstrong had recorded it earlier for RCA Victor, with His Dixieland Seven, on 17 October 1946.
Armstrong's rendition later served as the theme of the television series Frank's Place. Many other artists have recorded the song, among them Marilyn Maxwell (1947), Eddie Condon (1951), Frankie Laine (1954), Fats Domino (1958), Harry James (1958), Jonah Jones (1958), Pete Fountain (1959), Rick Nelson (1961), Al Hirt, Dinah Shore, Rosemary Clooney, Harry Connick Jr., and Joshua Redman featuring Gabrielle Cavassa (2023).
