You Do Something to Me is a 1929 show tune written by Cole Porter for the Broadway musical Fifty Million Frenchmen. In the original production it was performed by Genevieve Tobin and William Gaxton as Looloo Carroll and Peter Forbes, and it opens the show as Porter’s first fully integrated-book musical number. The song is structured with two verses and two choruses and is often described as a tender prequel to Let’s Do It, Let’s Fall in Love. It has been recorded by many artists over the years, including Lena Horne, Perry Como, Bing Crosby, Frank Sinatra, Ella Fitzgerald, Sinéad O’Connor, Bryan Ferry, Doris Day, Johnny Mathis and Marlene Dietrich. The piece remains a staple of the show tune genre and is associated with the Fifty Million Frenchmen soundtrack or cast album.